Tradename | Company | Number | Date | Products |
---|---|---|---|---|
PANDEL | ANI Pharmaceuticals | N-020453 DISCN | 1997-02-28 | 1 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
OTC monograph not final | 2012-08-24 | |
141016 hydrocortisone 0.5% / hydroquinone 4% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
141017 hydrocortisone 0.5% / hydroquinone 6% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
141060 hydrocortisone 0.5% / hydroquinone 4% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
141061 hydrocortisone 0.5% / hydroquinone 8% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
999 itch relieving | OTC monograph not final | 2016-11-14 |
advanced anti-itch therapy | OTC monograph not final | 2016-06-14 |
afassco 1% hydrocortisone | OTC monograph not final | 2023-01-12 |
aftate hydrocortisone cream | OTC monograph not final | 2016-03-31 |
ala-scalp | ANDA | 2025-01-08 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Inflammation | D007249 | MP_0001845 | — | — | — | 1 | 1 | 1 | 3 |
Conjunctivitis | D003231 | — | H10 | — | — | — | 1 | — | 1 |
Allergic conjunctivitis | D003233 | EFO_0007141 | H10.44 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cataract | D002386 | EFO_0001059 | H26.9 | — | 1 | 2 | — | 1 | 4 |
Uveitis | D014605 | EFO_1001231 | H20.9 | — | — | 1 | — | 1 | 2 |
Postoperative complications | D011183 | — | — | — | — | 1 | — | — | 1 |
Eye infections | D015817 | EFO_1001888 | — | — | — | 1 | — | — | 1 |
Drug common name | Hydrocortisone probutate |
INN | hydrocortisone |
Description | Cortisol is a 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses. It has a role as an anti-inflammatory drug, an anti-allergic agent, an anti-asthmatic drug, a human metabolite, a mouse metabolite and a drug allergen. It is a 21-hydroxy steroid, an 11beta-hydroxy steroid, a 20-oxo steroid, a 3-oxo-Delta(4) steroid, a primary alpha-hydroxy ketone, a tertiary alpha-hydroxy ketone, a 17alpha-hydroxy-C21-steroid and a glucocorticoid. It derives from a hydride of a pregnane. ... More |
Classification | Small molecule |
Drug class | cortisone derivatives |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CCCC(=O)O[C@]1(C(=O)COC(=O)CC)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C |
PDB | — |
CAS-ID | 72590-77-3 |
RxCUI | — |
ChEMBL ID | CHEMBL1200953 |
ChEBI ID | 31675 |
PubChem CID | 5754 |
DrugBank | DB00741 |
UNII ID | WI4X0X7BPJ (ChemIDplus, GSRS) |